MUSC

MUSC Nursing Jobs

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About Us

Who We Are

With roots in Charlston dating to 1824, the Medical University of South Carolina (MUSC) is the oldest medical school in the South. MUSC now educates more than 3,100 students in six colleges and trains over 950 residents each year. As South Carolina’s only comprehensive academic health system, MUSC has a mission to change what’s possible.

The 31,000 MUSC members are dedicated to delivering the highest-quality and safest patient care while fulfilling the goal of educating and training the next generation of care providers. It’s no wonder that MUSC nursing jobs are in demand. If you are considering one of the many MUSC careers open to dedicated nursing professionals, this is the place to start.

Interested in exploring MUSC jobs? Then you’ll want to know that as a nurse, your voice matters. You can take part in nurse-driven research, or help to improve daily practice by participating in the MUSC shared governance councils. Whether you are a dedicated clinician or are more focused on advancing the future of healthcare through research, there are MUSC jobs that may be a fit for you. You can find what ignites your passion working at:

  • Medical University Hospital Authority (MUHA), which employs care teams across the state
  • Medical University (UNIV), which is the state’s only integrated academic health sciences center
  • MUSC Physicians (MUSC-P), which includes physicians, advanced practice providers, clinicians, and non-clinical staff that provide care in the Charlston area

Whatever your area of expertise or preferred care setting, MUSC nurse jobs are opportunities to explore.

MUSC Nursing Jobs: Benefits

With an operating budget of $7.1 billion dollars and a world-class faculty, MUSC offers a wide variety of career paths and opportunities for nurses. No matter if you are starting out as a new grad RN or are an experienced nurse, you’ll find the culture at MUSC is based on a supportive team environment that ensures collaboration across disciplines.

Nurses can receive benefits and perks commensurate with the level of excellence MUSC maintains, including:

  • Competitive pay
  • Up to $25,00 towards student loan debt annually (for qualified team members)
  • Flexible insurance options, including dental and vision
  • Paid parental leave
  • Retirement plans that are right for you (supplemental or traditional)

Why Choose MUSC Nursing Jobs?

At the Medical University of South Carolina, the values of collaboration, compassion, innovation, integrity, and respect are at the heart of what staff does each day — and this commitment to providing outstanding patient care has been widely recognized. Some of the awards MUSC has received include:

  • #1 ranked hospital in South Carolina (US News, 2014–2024)
  • Magnet Designation (ANCC)
  • America’s Best-in-State Employers (Forbes, 2022)
  • America’s Best Large Employers (Forbes, 2023)
  • Diversity Champion (Insight Into Diversity Magazine, 2023)

Awards and recognition are valuable, but dedicated team members are what truly make a hospital system great. Find out what nursing means to this MUSC team member:

Recent Jobs
RN Med-Surg Full-time
MUSC

Registered Nurse (RN) - PRN Med/Surg Black River Medical Center

MUSC Cades, SC
Job Description Summary Come join our team at Black River Medical Center! Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ PRN Cost Center CC003452 BLR - Med-Surg (BRMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 8 Work Shift Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and environmental needs. This includes providing for the assessment, development of nursing diagnoses, outcome identification, planning, implementation of interventions, coordination of care, health teaching and promotion and evaluation of goals and interventions consistent with the policies of MUSC. Maintains a safe, therapeutic, and healing environment through ensuring patient privacy and responsive, respectful, accepting, and professional behavior. Demonstrates the ability to function in a professional setting through active participation in a professional practice model. This includes participating in shared governance, adherence to standards of care, participation in peer review and professional development promoting leadership and clinical excellence, effective team skills, autonomous practice and acknowledgment of accountability for actions and critical thinking. Coordinates the effective and efficient delivery of patient care services through the application of care management principles. Identifies clinical priorities and initiates action to improve patient outcomes. Demonstrates ability to function in a professional practice model through active participation in shared governance, promotion of a healthy work environment and acceptance of personal responsibility for professional growth. Additional Job Description License/Certification: South Carolina or Compact State RN License; American Heart Association BLS Certification Physical Requirements: 1. Ability to stand or sit for extended periods of time. 2. Proficiency in manual dexterity and fine motor skills for tasks such as taking patient vitals, administering injections, or conducting physical exams. 3. Capacity to lift and move patients or medical equipment as needed. 4. Visual acuity and color perception to accurately read medical charts, documents, and monitors. 5. Auditory ability to effectively communicate with patients and colleagues, as well as to perceive important sounds such as alarms or patient instructions. 6. Stamina and resilience to handle the physical and emotional demands of providing patient care, including long shifts and potentially stressful situations. 7. Mobility to navigate clinical environments, including moving between patient rooms, offices, and other areas of the facility. 8. Compliance with infection control protocols and proper use of personal protective equipment to maintain a safe and healthy work environment. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
RN ER Full-time
MUSC

Registered Nurse (RN) MUSC Black River Emergency Room - PRN

MUSC Cades, SC
Job Description Summary Awesome PRN opportunity for an experienced nurse interested in Emergency Services! Eligible to participate in the State Retirement Program. Apply today or contact Recruiter Shannon Shaw at shawsh@musc.edu or 843-674-2694 for more information. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ PRN Cost Center CC003476 BLR - Emergency (BRMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 8 Work Shift Job Description · Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). · Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. · Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and environmental needs. This includes providing for the assessment, development of nursing diagnoses, outcome identification, planning, implementation of interventions, coordination of care, health teaching and promotion and evaluation of goals and interventions consistent with the policies of MUSC. · Maintains a safe, therapeutic, and healing environment through ensuring patient privacy and responsive, respectful, accepting, and professional behavior. · Demonstrates the ability to function in a professional setting through active participation in a professional practice model. This includes participating in shared governance, adherence to standards of care, participation in peer review and professional development promoting leadership and clinical excellence, effective team skills, autonomous practice and acknowledgment of accountability for actions and critical thinking. · Coordinates the effective and efficient delivery of patient care services through the application of care management principles. Identifies clinical priorities and initiates action to improve patient outcomes. · Demonstrates ability to function in a professional practice model through active participation in shared governance, promotion of a healthy work environment and acceptance of personal responsibility for professional growth. Schedule: PRN as needed Additional Job Description Minimum Requirements: Associate's Degree, and experience as an ER RN required. Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current American Heart Association (AHA) Basic Life Support (BLS) certification or American Red Cross BLS for Healthcare Providers certification is required. Physical Requirements: 1. Ability to stand or sit for extended periods of time. 2. Proficiency in manual dexterity and fine motor skills for tasks such as taking patient vitals, administering injections, or conducting physical exams. 3. Capacity to lift and move patients or medical equipment as needed. 4. Visual acuity and color perception to accurately read medical charts, documents, and monitors. 5. Auditory ability to effectively communicate with patients and colleagues, as well as to perceive important sounds such as alarms or patient instructions. 6. Stamina and resilience to handle the physical and emotional demands of providing patient care, including long shifts and potentially stressful situations. 7. Mobility to navigate clinical environments, including moving between patient rooms, offices, and other areas of the facility. 8. Compliance with infection control protocols and proper use of personal protective equipment to maintain a safe and healthy work environment. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
RN Full-time
MUSC

Registered Nurse (RN) MUSC Leatherman Intake Unit - PRN

MUSC Florence, SC
Job Description Summary Awesome PRN opportunity for an experienced nurse interested in Behavioral Health! Eligible to participate in the State Retirement Program. Apply today or contact Recruiter Shannon Shaw at shawsh@musc.edu or 843-674-2694 for more information. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ PRN Cost Center CC005615 LBH - Intake Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 8 Work Shift Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and environmental needs. This includes providing for the assessment, development of nursing diagnoses, outcome identification, planning, implementation of interventions, coordination of care, health teaching and promotion and evaluation of goals and interventions consistent with the policies of MUSC. Maintains a safe, therapeutic, and healing environment through ensuring patient privacy and responsive, respectful, accepting, and professional behavior. Demonstrates the ability to function in a professional setting through active participation in a professional practice model. This includes participating in shared governance, adherence to standards of care, participation in peer review and professional development promoting leadership and clinical excellence, effective team skills, autonomous practice and acknowledgment of accountability for actions and critical thinking. Coordinates the effective and efficient delivery of patient care services through the application of care management principles. Identifies clinical priorities and initiates action to improve patient outcomes. Demonstrates ability to function in a professional practice model through active participation in shared governance, promotion of a healthy work environment and acceptance of personal responsibility for professional growth. Schedule: PRN as needed Additional Job Description Minimum Requirements: Associate's Degree, and a minimum of one year of work experience as a registered nurse required. Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current American Heart Association (AHA) Basic Life Support (BLS) certification or American Red Cross BLS for Healthcare Providers certification is required. Experience : RN experience required; Behavioral Health experience preferred Physical Requirements: 1. Ability to stand or sit for extended periods of time. 2. Proficiency in manual dexterity and fine motor skills for tasks such as taking patient vitals, administering injections, or conducting physical exams. 3. Capacity to lift and move patients or medical equipment as needed. 4. Visual acuity and color perception to accurately read medical charts, documents, and monitors. 5. Auditory ability to effectively communicate with patients and colleagues, as well as to perceive important sounds such as alarms or patient instructions. 6. Stamina and resilience to handle the physical and emotional demands of providing patient care, including long shifts and potentially stressful situations. 7. Mobility to navigate clinical environments, including moving between patient rooms, offices, and other areas of the facility. 8. Compliance with infection control protocols and proper use of personal protective equipment to maintain a safe and healthy work environment. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
RN New Grad Full-time
MUSC

Registered Nurse I (Fall 2026 New Grad Blitz) - Adult Cardiac Cath Lab

MUSC Charleston, SC
Job Description Summary The MUSC Cardiac Cath Lab consists of five state of the art labs plus one hybrid OR supported by a Prep and Recovery unit. We provide advanced cardiac catheterization care for heart attack, stroke and coronary artery disease, including chronic total coronary occlusion, alcohol septal ablation, patent foramen ovale and atrial septal defect. We continue to expand our Heart Failure program and are the largest transplant facility in South Carolina. MUSC Health also offers more treatment options for heart valve disease than any other center in the state, including minimally invasive TAVR, MitraClip and TEER approaches. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000305 CHS - Cardio Cath - Adult (ART) Pay Rate Type Hourly Pay Grade Health-27 Scheduled Weekly Hours 40 Work Shift Job Description The application deadline to apply for this unit is August 5, 2026. Hours Per Week : 40 Scheduled Work Hours/Shift: 4-10 hour shifts. Shifts vary based on the needs of the department. Job Summary/Purpose : Under general supervision, the Registered Nurse I (New Graduate) assists at the advanced beginner level in providing individualized, goal directed nursing care to patients and families utilizing principles and practices of the nursing process; interacts with other members of the health care team to achieve desired outcomes. Minimum Training and Education : Bachelor of Nursing degree preferred. RN staff hired on or after July 1, 2013 with an Associate or Diploma degree in nursing are required to be enrolled in an accredited BSN program within two years and successfully obtain a BSN degree within four years of the RN hire or reclassification date. Required Licensure, Certifications, and Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required, either a certification from an American Heart Association (AHA) BLS for Healthcare Providers (or AHA recognized equivalent) or an American Red Cross CPR/AED for Professional Rescuer and Healthcare Provider. Additional Job Description Physical and Mental Requirements : Ability to perform job functions while standing. (Continuous) Ability to perform job functions while sitting. (Continuous) Ability to perform job functions while walking. (Continuous) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work outside in temperature extremes. (Infrequent) Ability to work from elevated areas. (Frequent) Ability to work in confined/cramped spaces. (Frequent) Ability to perform job functions from kneeling positions. (Infrequent) Ability to bend at the waist. (Continuous) Ability to twist at the waist. (Frequent) Ability to squat and perform job functions. (Frequent) Ability to perform "pinching" operations. (Frequent) Ability to perform gross motor activities with fingers and hands. (Continuous) Ability to perform firm grasping with fingers and hands. (Continuous) Ability to perform fine manipulation with fingers and hands. (Continuous) Ability to reach overhead. (Frequent) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to use lower extremities for balance and coordination. (Frequent) Ability to reach in all directions. (Continuous) Ability to lift and carry 50 lbs. unassisted. (Infrequent) Ability to lift/lower objects 50 lbs. from/to floor from/to 36 inches unassisted. (Infrequent) Ability to lift from 36" to overhead 25 lbs. (Infrequent) Ability to exert up to 50 lbs. of force. (Frequent) Examples include: To transfer a 100 lb. patient that cannot assist in the transfer requires 50 lbs. of force. For every 100 additional pounds, assistance will be required from another healthcare worker. 20 lbs. of force is needed to push a 400 lb. patient in a wheelchair on carpet. 25 lbs. of force is required to push a stretcher with a patient with one hand. Ability to maintain 20/40 vision, corrected, in one eye or with both eyes. (Continuous) Ability to see and recognize objects close at hand or at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to deal effectively with stressful situations. (Continuous) Ability to work rotating shifts. (Frequent) Ability to work overtime as required. (Frequent) Ability to work in a latex safe environment. (Continuous) Ability to maintain tactile sensory functions. (Continuous) (Selected Positions) *Ability to maintain good olfactory sensory function. (Continuous) *(Selected Positions) *Ability to be qualified physically for respirator use, initially and as required. (Continuous) (Selected Positions) If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
RN Full-time
MUSC

Registered Nurse ll - ART EP Lab

MUSC Charleston, SC
Job Description Summary Job Description Summary Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000484 CHS - Lab - EP (ART) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Day (United States of America) Job Description Hours Per Week : 36 Scheduled Work Hours/Shift: Monday-Friday. 3 - 12 hour shifts; call back occasionally Job Summary/Purpose : Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Minimum Training and Education : Bachelor of Nursing degree preferred. RN staff hired on or after July 1, 2013 with an Associate or Diploma degree in nursing are required to be enrolled in an accredited BSN program within two years and successfully obtain a BSN degree within four years of the RN hire or reclassification date. Refer to policy A141 for more details. A minimum of one year of work experience as a registered nurse required. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required, either a certification from an American Heart Association (AHA) BLS for Healthcare Providers (or AHA recognized equivalent) or an American Red Cross CPR/AED for Professional Rescuer and Healthcare Provider. Additional Job Description Physical and Mental Requirements : Ability to perform job functions while standing. (Continuous) Ability to perform job functions while sitting. (Continuous) Ability to perform job functions while walking. (Continuous) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work outside in temperature extremes. (Infrequent) Ability to work from elevated areas. (Frequent) Ability to work in confined/cramped spaces. (Frequent) Ability to perform job functions from kneeling positions. (Infrequent) Ability to bend at the waist. (Continuous) Ability to twist at the waist. (Frequent) Ability to squat and perform job functions. (Frequent) Ability to perform "pinching" operations. (Frequent) Ability to perform gross motor activities with fingers and hands. (Continuous) Ability to perform firm grasping with fingers and hands. (Continuous) Ability to perform fine manipulation with fingers and hands. (Continuous) Ability to reach overhead. (Frequent) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to use lower extremities for balance and coordination. (Frequent) Ability to reach in all directions. (Continuous) Ability to lift and carry 50 lbs. unassisted. (Infrequent) Ability to lift/lower objects 50 lbs. from/to floor from/to 36 inches unassisted. (Infrequent) Ability to lift from 36" to overhead 25 lbs. (Infrequent) Ability to exert up to 50 lbs. of force. (Frequent) Examples include: To transfer a 100 lb. patient that can not assist in the transfer requires 50 lbs. of force. For every 100 additional pounds, assistance will be required from another healthcare worker. 20 lbs. of force is needed to push a 400 lb. patient in a wheelchair on carpet. 25 lbs. of force is required to push a stretcher with a patient with one hand. Ability to maintain 20/40 vision, corrected, in one eye or with both eyes. (Continuous) Ability to see and recognize objects close at hand or at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to deal effectively with stressful situations. (Continuous) Ability to work rotating shifts. (Frequent) Ability to work overtime as required. (Frequent) Ability to work in a latex safe environment. (Continuous) Ability to maintain tactile sensory functions. (Continuous) (Selected Positions) *Ability to maintain good olfactory sensory function. (Continuous) *(Selected Positions) *Ability to be qualified physically for respirator use, initially and as required. (Continuous) (Selected Positions) If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
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